Inhibition of lipid synthesis by clofibrate: comparative study of human skin, rat skin, and rat liver in vitro
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منابع مشابه
Inhibition of lipid synthesis by clofibrate: comparative study of human skin, rat skin, and rat liver in vitro.
The effects of clofibrate (ethyl p-chlorophenoxyisobutyrate) on lipid synthesis by human skin were studied in vitro. The drug was found to inhibit lipid synthesis from [1-(14)C]acetate or [U-(14)C]glucose. While the synthesis of all classes of lipids was suppressed, inhibition of sterol synthesis was more pronounced than that of fatty acids and glycerides. By comparison, sodium p-chlorophenoxyi...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1972
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)39440-2